Ouralusouralus

Species-specific research literature

Glutathione in dogs, cats, horses

The veterinary literature below concerns endogenous glutathione status as a biomarker, and precursors — N-acetylcysteine, SAMe, glycine, ribose-cysteine. It is not literature on exogenous glutathione, which is what the catalog lists.

This page summarises what the published literature covers, and what it does not. It is a bibliography with context, not guidance: Ouralus makes no statement about the use of this compound in any animal, and nothing here is a veterinary recommendation. For laboratory research use only. Not for human consumption.

Scope of the literature

Species studied
dogs, cats, horses
Records cited
13
How these were found
PubMed, scoped by MeSH species check-tags (Dogs, Cats, Horses). Rodent-only literature was excluded by construction. Every record listed here was re-fetched from NCBI and checked to resolve.

Primary in-vivo studies

Studies carried out in the species named, in living animals.

  1. Liver glutathione concentrations in dogs and cats with naturally occurring liver disease.Am J Vet Res · 2002 · dogs, catsPMID 12171175 ↗
  2. Glutathione, cysteine, and ascorbate concentrations in clinically ill dogs and cats.J Vet Intern Med · 2009 · dogs, catsPMID 19143933 ↗
  3. Reactive oxygen species, glutathione, and vitamin E concentrations in dogs with hemolytic or nonhemolytic anemia.J Vet Intern Med · 2020 · dogsPMID 33047374 ↗
  4. Safety and efficacy of a ribose-cysteine supplement to increase erythrocyte glutathione concentration in healthy dogs.Am J Vet Res · 2021 · dogsPMID 34296936 ↗
  5. Glycine supplementation can partially restore oxidative stress-associated glutathione deficiency in ageing cats.Br J Nutr · 2024 · catsPMID 38418414 ↗
  6. S-adenosylmethionine (SAMe) in a feline acetaminophen model of oxidative injury.J Feline Med Surg · 2003 · catsPMID 12670431 ↗
  7. Clinicopathologic evaluation N-acetylcysteine therapy in acetaminophen toxicosis in the cat.Am J Vet Res · 1981 · catsAcetaminophen toxicosis induced in cats; the agent studied was N-acetylcysteine, a precursor. Endpoint was erythrocyte GSH depletion — directly supports the endogenous-and-precursor-scope caveat.PMID 7337295 ↗
  8. Pharmacokinetics of N-acetylcysteine after oral and intravenous administration to healthy cats.Am J Vet Res · 2013 · catsPMID 23363356 ↗
  9. Serum vitamin E and blood glutathione peroxidase values of horses with degenerative myeloencephalopathy.Am J Vet Res · 1989 · horsesPMID 2919821 ↗
  10. Immune sensitization of equine bronchus: glutathione, IL-1beta expression and tissue responsiveness.Respir Res · 2005 · horsesPMID 16164745 ↗
  11. Effects of ozone and airway inflammation on glutathione status and iron homeostasis in the lungs of horses.Am J Vet Res · 1996 · horsesPMID 8874733 ↗
  12. Blood glutathione status and activity of glutathione-metabolizing antioxidant enzymes in erythrocytes of young trotters in basic training.J Anim Physiol Anim Nutr (Berl) · 2010 · horsesPMID 19364380 ↗
  13. Glutathione content and glutathione peroxidase expression in in vivo and in vitro matured equine oocytes.Mol Reprod Dev · 2006 · horsesPMID 16493673 ↗

What this page does not establish

Clinical veterinary literature: hepatic GSH in dogs and cats with naturally occurring liver disease, GSH depletion in critically ill animals, an RCT of a cysteine precursor in healthy dogs, glycine in senior cats, GSH status in horses.

Research-literature characterization, provided for research context only. For laboratory research use only. Not for human consumption.

Product record: Glutathione