BPC-157 and GHK-Cu: what the research literature examines
BPC-157 and GHK-Cu are different molecules with different sequences and different molar masses. This page sets out what each published literature examines, in what study material, and what each current lot assayed. It does not say which is preferable for any purpose, and nothing on this site does.
Identity, side by side
| Property | BPC-157 | GHK-Cu |
|---|---|---|
| What it is | Synthetic 15–amino-acid peptide (pentadecapeptide) | Copper(II) complex of a synthetic 3–amino-acid peptide (tripeptide) |
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val | Gly-His-Lys |
| CAS | 137525-51-0 | 89030-95-5 |
| Molecular formula | C62H98N16O22 | C14H22CuN6O4 |
| Molar mass | 1419.5 g/mol | 401.91 g/mol |
| Research areas in the literature | Tissue repair models, Angiogenesis, Cytoprotection, Extracellular matrix | Extracellular matrix, Tissue repair models, Cytoprotection, Angiogenesis |
Shared research areas: Tissue repair models, Angiogenesis, Cytoprotection, Extracellular matrix. A shared area means the two are examined in the same field of study — not that they are examined through the same mechanism, and not that findings for one transfer to the other.
What each literature examines
The characterization below reflects published research literature only. It describes what that literature examines; it is not a statement about use in people. Both compounds are investigational research material and neither is an approved product.
BPC-157
BPC-157 appears in tissue-repair and angiogenesis models, where the reported endpoints are blood-vessel formation and nitric-oxide–system signalling.2378214529998800
Study material
Rodent preparations and cell assays; the angiogenesis strand is largely endothelial cell work and rodent vessel assay.2378214529998800
GHK-Cu
GHK-Cu appears in extracellular-matrix and cytoprotection models as a copper-coordinating tripeptide, with reported endpoints in collagen and matrix-protein expression and in oxidative-stress assays.1864422522666519
Study material
Cell culture predominates — fibroblast and keratinocyte preparations — with rodent models in the oxidative-stress and lung work.2623673035936787
Purity, and how to check both yourself
Purity here is a measurement, not a position. Each lot currently shipping was analysed by an independent laboratory by HPLC for identity. We do not test our own material. Both certificates state an assayed purity figure.
| Measurement | BPC-157 | GHK-Cu |
|---|---|---|
| Assayed purity, current lot | 99.497% | 99.959% |
| Testing laboratory | Janoshik | Janoshik |
| Lot | Blue Transparent Cap / Silver Crimp | Not stated on report |
| Verify key | RMAIPH836PXJ | FFU7FYYJNJ9V |
Enter either verify key at janoshik.com/verify and the laboratory returns the report it issued for that batch. You are confirming the result with them, not with us. Full certificates: BPC-157 · GHK-Cu
We report HPLC identity and assayed purity only. We do not run heavy-metal, microbial, endotoxin, or sterility analysis, and we do not claim it anywhere on this site.
Cited literature
- BPC 157 and blood vesselsSeiwerth S, et al. · Current Pharmaceutical Design · 2014PMID 23782145 ↗
- BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone HealingSeiwerth S, et al. · Current Pharmaceutical Design · 2018PMID 29998800 ↗
- The human tri-peptide GHK and tissue remodelingPickart L · Journal of Biomaterials Science, Polymer Edition · 2008PMID 18644225 ↗
- The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of agingPickart L, et al. · Oxidative Medicine and Cellular Longevity · 2012PMID 22666519 ↗
- GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin RegenerationPickart L, Vasquez-Soltero JM, Margolina A · BioMed Research International · 2015PMID 26236730 ↗
- Glycyl-L-histidyl-L-lysine-Cu2+ attenuates cigarette smoke-induced pulmonary emphysema and inflammation by reducing oxidative stress pathwayZhang Q, et al. · Frontiers in Molecular Biosciences · 2022PMID 35936787 ↗
Research-literature characterization, provided for research context only. For laboratory research use only. Not for human consumption.