Janoshik tested
99.402%

FormLyophilized powder
Quantity10 mg
Puritythird-party HPLC-tested

Research peptide · Ref. P03

TB-500

Name: Ouralus TB-500
Brand: Ouralus
SKU: P03
Price: 70.00 USD
Availability: InStock

Synthetic peptide · 10 mg vial

A synthetic N-acetylated heptapeptide corresponding to the actin-binding region of thymosin β4. Examined in the literature in the context of cytoskeletal dynamics and cell motility.

Choose your optionSingle vial10 mg$7010-vial kit10 × 10 mg · save 20%$562

How many

1Single vialMost popular22 vialsBest value3+3 or more

Multi-vial pricing for TB-500 is applied by the order system at checkout. This page selects a quantity; it does not quote a rate it cannot honour.

$70Single vial · 10 mg

Same-day dispatch on orders before 11am CSTBusiness days
Typically arrives 2–5 business days after dispatchCarrier estimate, not a guaranteed date
Shipment protection includedNo additional charge at checkout

For laboratory research use only. Not for human consumption.

99.4%HPLC assayed purity
Third-party testedJanoshik, per batch
View certificate ↓Full report + verify key

Characterization

What it is, stated plainly.

What it is

A synthetic N-acetylated heptapeptide (Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH) corresponding to the actin-binding region of thymosin β4, a 43-residue actin-sequestering protein. It is a fragment, not the intact protein. Published work sits in the actin-dynamics and cell-migration literature.

How a lot is verified

Identity confirmed by HPLC and mass-spec; purity assayed by third-party HPLC, with a certificate of analysis published where tested. A lot that misses spec is rejected.

Handling & storage

Supplied as a lyophilized powder. Store at −20°C, desiccated and protected from light. Handled per the receiving laboratory's protocols. Not for human consumption.

Specifications

Research specifications.

Form: Lyophilized powder
Quantity: 10 mg
Purity: third-party HPLC-tested
CAS: 885340-08-9
Molecular formula: C38H68N10O14
Storage: −20°C, desiccated

A CAS number or molecular formula is shown only where it has been verified. Where one is not shown, it has not been, and none is implied.

Research background

What the literature reports.

CAS: 885340-08-9
Molecular formula: C38H68N10O14
Molar mass: 889 g/mol
Sequence: Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH
PubChem CID: 62707662
UNII: QHK6Z47GTG

Also known asTB 500 · TB500 · Ac-LKKTETQ · N-Acetyl thymosin β4 (17-23) fragment

"TB-500" is the common name for a synthetic, N-acetylated peptide fragment (Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln) corresponding to an actin-binding region of thymosin beta-4, supplied as a lyophilized powder for laboratory research use only.

Material sold as "TB-500" is not always the same molecule — some suppliers provide full-length thymosin beta-4 — so identity should be confirmed against each lot's mass-spec / HPLC data. Ouralus provides a third-party certificate of analysis published where tested.

Tissue repair models
Extracellular matrix

Handling & stability

Lyophilized: −20°C · 24 months (sealed, desiccated)
Reconstituted: 2–8°C · weeks (research handling)

Solvent · laboratory handlingBacteriostatic water. Reconstitution parameters are a laboratory-handling matter determined by the researcher; no in-vivo or human-use parameters are provided.

Selected literature

Thymosin beta 4 interactionsBubb MR · Vitamins and Hormones · 2003PMID 12852258 ↗
beta-ThymosinsHannappel E · Annals of the New York Academy of Sciences · 2007PMID 17468232 ↗
The beta-thymosin enigmaSun HQ, et al. · Annals of the New York Academy of Sciences · 2007PMID 17495248 ↗
Thymosin beta4 and its posttranslational modificationsHannappel E · Annals of the New York Academy of Sciences · 2010PMID 20536447 ↗
Potential role of thymosin Beta 4 in liver fibrosisKim J, et al. · International Journal of Molecular Sciences · 2015PMID 26006229 ↗
Thymosin Beta 4 Is a Potential Regulator of Hepatic Stellate CellsKim J, et al. · Vitamins and Hormones · 2016PMID 27450733 ↗
Cardioprotection by Thymosin Beta 4Pipes GT, et al. · Vitamins and Hormones · 2016PMID 27450736 ↗
Thymosin Beta-4 Modulates Cardiac Remodeling by Regulating ROCK1 Expression in Adult MammalsMaar K, et al. · International Journal of Molecular Sciences · 2025PMID 40362372 ↗

Read the full TB-500 research reference →

Research-literature characterization, provided for research context only. For laboratory research use only. Not for human consumption.

How we verify TB-500

The certificate, before the claim.

COA for every tested lotPublished with its batch number and assay date
Verify keys you can check12 characters, confirmed on the lab's own site
CardSecure checkout
Flat $10.60 shippingFree over $150 · same-day if ordered by 11am CST

View the full certificate of analysis for TB-500 →Sample certificate · illustrative format

Identity: HPLC + mass-spec confirmation
Purity (assay): Third-party HPLC
Appearance: White lyophilized powder
Certificate of analysis: Published where tested

Format is illustrative. We present no assay %, residual-solvent, or lot figures until a real batch is tested and its certificate published. For laboratory research use only. See our full standard →

Questions

Answered straight.

What is TB-500?

"TB-500" is the common name for a synthetic N-acetylated peptide fragment (Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln) corresponding to an actin-binding region of thymosin beta-4. Ouralus supplies it as a lyophilized powder for laboratory research use only, with a third-party HPLC certificate of analysis published where tested.

Is TB-500 the same as thymosin beta-4?

Not necessarily. The name "TB-500" is used in the market for both this short synthetic fragment and, by some suppliers, full-length thymosin beta-4. Because there is no single compendial standard tying the name to one molecule, confirm identity against the lot's certificate of analysis and mass-spec data.

Who can order?

These materials are supplied strictly for laboratory and research use, to purchasers of legal age. They are not supplements, drugs, or foods, and are not for human or animal consumption.

Is TB-500 legal to buy?

TB-500 is supplied strictly as a research chemical for laboratory research use only — it is not a drug, supplement, or food, and not for human or animal consumption. It ships to purchasers of legal age for research use. Buyers are responsible for compliance with the laws that apply to research materials in their own jurisdiction.

Is a certificate of analysis provided with TB-500?

Yes — each tested lot of TB-500 ships with a third-party HPLC certificate of analysis from Janoshik, independently verifiable by lot (verify key PDXV8UJEL1G4). The current lot assayed 99.402%. We publish the certificate before making any purity claim; this is a research chemical for laboratory use only.

TB-500$70