Epitalon: compound identifiers, research literature, and verified purity
99.154%assayed by HPLC at Janoshik
The Janoshik report assayed 99.154% by third-party HPLC, and that report is published here with a key you can confirm with the laboratory yourself.
Compound identifiers
- CAS
- 307297-39-8
- Molecular formula
- C14H22N4O9
- Molar mass
- 390.35 g/mol
- Sequence
- Ala-Glu-Asp-Gly
- PubChem CID
- 219042
- UNII
- O65P17785G
Also known asEpithalon · Epithalone · AEDG peptide · Alanyl-glutamyl-aspartyl-glycine
What the research literature covers
The characterization below reflects published research literature only. It describes what that literature examines; it is not a statement about use in people. Epitalon is investigational research material and is not an approved product.
Epitalon (also epithalon; Ala-Glu-Asp-Gly) is a synthetic tetrapeptide modeled on the pineal peptide preparation epithalamin, supplied as a lyophilized powder for laboratory research use only.
It is studied in the research literature in the context of telomere biology and cellular-senescence models. Note that PubChem merges several CAS numbers onto this entry, one of which historically refers to the distinct natural extract epithalamin.
Reported mechanism · literatureReported in cell-based research in association with telomerase-activity and telomere-length endpoints; the summary reflects that literature only.
- Telomere biology
- Cellular senescence
Epitalon and NAD +, side by side
These two are frequently discussed together. They are different molecules, with different sequences and different molar masses. The table states what each one is and what its latest published report assayed. It does not say which is preferable for any purpose, and nothing on this site does.
| Property | Epitalon | NAD + |
|---|---|---|
| What it is | Synthetic 4–amino-acid peptide (tetrapeptide) | Dinucleotide redox coenzyme — not a peptide |
| CAS | 307297-39-8 | 53-84-9 |
| Molar mass | 390.35 g/mol | 663.43 g/mol |
| Research areas in the literature | Telomere biology, Cellular senescence | Mitochondrial biology, Metabolic signalling, Cellular senescence |
| Verify key | 4371ZNKCLG9H | VC63IEZ7H6YF |
Purity, and how to check it yourself
Purity here is a measurement, not a position. A report from Janoshik, an independent laboratory, is published for Epitalon: assayed purity and net content. We do not test our own material.
- Lot
- Green
- Analysed
- January 19, 2026
- Assayed purity
- 99.154%
- Testing laboratory
- Janoshik
- Verify key
- 4371ZNKCLG9H
Enter that key at janoshik.com/verify and the laboratory returns the report it issued for this batch. You are confirming the result with them, not with us. The full certificate is published as a report image on the Epitalon certificate page.
We report assayed purity and net content only. We do not run heavy-metal, microbial, endotoxin, or sterility analysis, and we do not claim it anywhere on this site.
Handling and stability
- Lyophilized
- −20°C · 24 months (sealed, desiccated)
Questions
What is Epitalon?
Epitalon (epithalon) is a synthetic tetrapeptide, Ala-Glu-Asp-Gly, modeled on the pineal preparation epithalamin. Ouralus supplies it as a lyophilized powder for laboratory research use only, with a third-party HPLC certificate of analysis published where tested.
What is the sequence and formula of Epitalon?
The sequence is Ala-Glu-Asp-Gly (AEDG), molecular formula C14H22N4O9 (molar mass ≈ 390.4 g/mol; PubChem CID 219042, primary CAS 307297-39-8).
Is Epitalon third-party tested?
Yes. A report from Janoshik, an independent laboratory, is published for Epitalon; it prints an assayed purity of 99.154%. Its batch field matches the lot currently shipping. The certificate carries verify key 4371ZNKCLG9H, which you can confirm directly at janoshik.com/verify.
Is Epitalon an approved product?
No. Epitalon is supplied strictly as a research chemical for laboratory research use only. It is not a drug, not a supplement, and not a food, and it is not for human or animal consumption.
Selected literature
- AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic MechanismKhavinson V, et al. · Molecules · 2020PMID 32019204 ↗
- Overview of Epitalon — Highly Bioactive Pineal Tetrapeptide with Promising PropertiesAraj SK, et al. · International Journal of Molecular Sciences · 2025PMID 40141333 ↗
- Peptide Epitalon activates chromatin at the old ageKhavinson VKh, et al. · Neuro Endocrinology Letters · 2003PMID 14647006 ↗
- Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNAFedoreyeva LI, et al. · Biochemistry (Moscow) · 2011PMID 22117547 ↗
Research-literature characterization, provided for research context only. For laboratory research use only. Not for human consumption.