Semax: identity, research literature, and verified purity
99.184%assayed by HPLC at Janoshik
The lot currently shipping assayed 99.184% by third-party HPLC at Janoshik, and that certificate is published here with a key you can confirm with the laboratory yourself.
Identity and registry data
- CAS
- 80714-61-0
- Molecular formula
- C37H51N9O10S
- Molar mass
- 813.92 g/mol
- Sequence
- Met-Glu-His-Phe-Pro-Gly-Pro
- PubChem CID
- 9811102
- UNII
- I5FAL2585H
Also known asACTH(4-7)-Pro-Gly-Pro · MEHFPGP · ACTH (4-10) heptapeptide analog
What the research literature covers
The characterization below reflects published research literature only. It describes what that literature examines; it is not a statement about use in people. Semax is investigational research material and is not an approved product.
Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) modeled on a fragment of adrenocorticotropic hormone (ACTH 4-7) extended with a Pro-Gly-Pro tail, supplied as a lyophilized powder for laboratory research use only.
In the literature it is studied in neurochemistry research models and for its metal-ion (copper / zinc) coordination chemistry; the characterization here reflects that research literature only.
Reported mechanism · literatureStudied in the research literature in the context of melanocortin-related signalling and neuromodulation models; the summary reflects that literature only.
- Neuroprotection models
- Melanocortin signalling
Purity, and how to check it yourself
Purity here is a measurement, not a position. The lot currently shipping was analysed by Janoshik, an independent laboratory, by HPLC for identity and assayed purity. We do not test our own material.
- Lot
- Clear Cap
- Analysed
- May 28, 2026
- Assayed purity
- 99.184%
- Testing laboratory
- Janoshik
- Verify key
- LI1FR3Y5KSVB
Enter that key at janoshik.com/verify and the laboratory returns the report it issued for this batch. You are confirming the result with them, not with us. The full certificate is published as a PDF on the Semax certificate page.
We report HPLC identity and assayed purity only. We do not run heavy-metal, microbial, endotoxin, or sterility analysis, and we do not claim it anywhere on this site.
Handling and stability
- Lyophilized
- −20°C · 24 months (sealed, desiccated)
- Reconstituted
- 2–8°C · weeks (research handling)
Reconstitution solvent: sterile bacteriostatic water. Reconstitution parameters are a laboratory-handling matter determined by the researcher; no in-vivo or human-use parameters are provided. The concentration arithmetic for a reconstituted research solution is available in our reconstitution calculator.
Questions
What is Semax?
Semax is a synthetic heptapeptide derived from an ACTH(4-7) fragment with a Pro-Gly-Pro extension. Ouralus supplies it as a lyophilized powder for laboratory research use only, with a third-party HPLC certificate of analysis published where tested.
What is the sequence of Semax?
The base Semax heptapeptide is Met-Glu-His-Phe-Pro-Gly-Pro (free acid), molecular formula C37H51N9O10S (PubChem CID 9811102, CAS 80714-61-0). An N-acetylated variant is a distinct related compound.
Is Semax third-party tested?
Yes. The lot currently shipping was analysed by Janoshik, an independent laboratory, by HPLC for identity and assayed purity, and assayed 99.184%. The certificate carries verify key LI1FR3Y5KSVB, which you can confirm directly at janoshik.com/verify.
Is Semax an approved product?
No. Semax is supplied strictly as a research chemical for laboratory research use only. It is not a drug, not a supplement, and not a food, and it is not for human or animal consumption.
Selected literature
- Semax, an ACTH(4-10) analogue with nootropic properties, activates dopaminergic and serotoninergic brain systems in rodentsEremin KO, et al. · Neurochemical Research · 2005PMID 16362768 ↗
- Influence of the N-terminus acetylation of Semax on copper(II) and zinc(II) coordination and biological propertiesMagrì A, et al. · Journal of Inorganic Biochemistry · 2016PMID 27586814 ↗
Research-literature characterization, provided for research context only. For laboratory research use only. Not for human consumption.