Ouralusouralus
Compound reference

Ipamorelin: identity and research literature

Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2), CAS 170851-70-4. Ouralus supplies it as a lyophilized powder for laboratory research use only. No third-party certificate of analysis has been published for this compound yet, so no purity figure is claimed for it and its identity and purity remain unconfirmed.

Identity and registry data

CAS
170851-70-4
Molecular formula
C38H49N9O5
Molar mass
711.85 g/mol
Sequence
Aib-His-D-2Nal-D-Phe-Lys-NH2
PubChem CID
9831659
UNII
Y9M3S784Z6

Also known asNNC 26-0161 · NNC-260161 · Ipamorelin acetate

What the research literature covers

The characterization below reflects published research literature only. It describes what that literature examines; it is not a statement about use in people. Ipamorelin is investigational research material and is not an approved product.

Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) described in the literature as one of the earliest selective growth-hormone secretagogues, supplied as a lyophilized powder for laboratory research use only.

It is studied in the research literature in growth-hormone-axis models; the characterization here reflects that literature only.

Reported mechanism · literatureDescribed in the research literature as a selective growth-hormone secretagogue studied in growth-hormone-axis models; the summary reflects that literature only.

  • Growth hormone axis

Purity, and why none is claimed here

Purity here is a measurement, not a position — and no measurement has been published for Ipamorelin. No third-party certificate of analysis exists for it yet, so this page states no assayed purity, no lot, and no verify key for it. Its identity and purity remain unconfirmed.

The standard does not change: lots are analysed by an independent laboratory by HPLC for identity and assayed purity, and the certificate is published with a key you can confirm at janoshik.com/verify yourself. We do not test our own material, and we do not claim a figure before its report exists. Those numbers appear here when a report does.

We report HPLC identity and assayed purity only. We do not run heavy-metal, microbial, endotoxin, or sterility analysis, and we do not claim it anywhere on this site.

Handling and stability

Lyophilized
−20°C · 24 months (sealed, desiccated)
Reconstituted
2–8°C · weeks (research handling)

Reconstitution solvent: sterile bacteriostatic water. Reconstitution parameters are a laboratory-handling matter determined by the researcher; no in-vivo or human-use parameters are provided. The concentration arithmetic for a reconstituted research solution is available in our reconstitution calculator.

Questions

What is Ipamorelin?

Ipamorelin is a synthetic pentapeptide and one of the earliest selective growth-hormone secretagogues reported in the literature. Ouralus supplies it as a lyophilized powder for laboratory research use only, with a third-party HPLC certificate of analysis published where tested.

What is the amino-acid sequence of Ipamorelin?

The reported sequence is Aib-His-D-2-Nal-D-Phe-Lys-NH2 (Aib = α-aminoisobutyric acid; C-terminal amide), molecular formula C38H49N9O5 (PubChem CID 9831659, CAS 170851-70-4).

Is Ipamorelin third-party tested?

Not yet. No third-party certificate of analysis has been published for Ipamorelin, so no purity figure is claimed for it and its identity and purity remain unconfirmed. Ouralus HPLC-tests its catalogue lots and publishes each certificate with a verify key confirmable at janoshik.com/verify as the report is finalized; this page will carry those figures once a report exists for this compound.

Is Ipamorelin an approved product?

No. Ipamorelin is supplied strictly as a research chemical for laboratory research use only. It is not a drug, not a supplement, and not a food, and it is not for human or animal consumption.

Selected literature

  1. Ipamorelin, the first selective growth hormone secretagogueRaun K, et al. · European Journal of Endocrinology · 1998PMID 9849822 ↗
  2. A new series of highly potent growth hormone-releasing peptides derived from ipamorelinAnkersen M, et al. · Journal of Medicinal Chemistry · 1998PMID 9733495 ↗
  3. Pharmacokinetic evaluation of ipamorelin and other peptidyl growth hormone secretagogues with emphasis on nasal absorptionJohansen PB, et al. · Xenobiotica · 1998PMID 9879640 ↗
  4. Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in ratsJohansen PB, et al. · Growth Hormone & IGF Research · 1999PMID 10373343 ↗
  5. The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female ratsSvensson J, et al. · The Journal of Endocrinology · 2000PMID 10828840 ↗
  6. The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation of adult ratsAndersen NB, et al. · Growth Hormone & IGF Research · 2001PMID 11735244 ↗
  7. Mechanism of ipamorelin-evoked insulin release from the pancreas of normal and diabetic ratsAdeghate E, et al. · Neuroendocrinology Letters · 2004PMID 15665799 ↗
  8. Efficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileusGreenwood-Van Meerveld B, et al. · Journal of Experimental Pharmacology · 2012PMID 27186127 ↗

Research-literature characterization, provided for research context only. For laboratory research use only. Not for human consumption.